Actively Recruiting

Phase Not Applicable
Age: 40Years +
All Genders
NCT06482333

Timing of Resumption of Direct Oral Anticoagulants Following Polypectomy

Led by The University of Hong Kong · Updated on 2026-05-01

194

Participants Needed

1

Research Sites

169 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this prospective randomized non-inferiority trial is to compare two different resumption time of Direct Oral Anticoagulants (DOACs) after colonoscopic polypectomy. We hypothesize that early resumption of DOACs after colonoscopy and polypectomy is associated with comparable post-polypectomy bleeding rate to those with delayed resumption. This study aims to compare the post-polypectomy bleeding risk of two different timing of resuming DOACs (Day 0 vs Day 2):

CONDITIONS

Official Title

Timing of Resumption of Direct Oral Anticoagulants Following Polypectomy

Who Can Participate

Age: 40Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults taking Direct Oral Anticoagulants (DOACs) scheduled for elective colonoscopy
  • Patients who have a complete colonoscopy with polypectomy performed
Not Eligible

You will not qualify if you...

  • Previous surgery removing any part of the colon
  • Having inflammatory bowel disease or polyposis syndrome
  • Presence of large polyps requiring advanced removal procedures such as endoscopic submucosal dissection
  • Immediate bleeding during polypectomy that requires treatment
  • Patients without polypectomy performed
  • Patients without complete colonoscopy done

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Queen Mary Hospital, the University of Hong Kong

Hong Kong, Hong Kong

Actively Recruiting

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Research Team

W

Wai Keung Leung

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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