Actively Recruiting
Timing of Subcostal TAPB Combined With Rectus Sheath Block for Postoperative Pain After Laparoscopic Cholecystectomy
Led by Eulji University Hospital · Updated on 2026-02-27
96
Participants Needed
1
Research Sites
46 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This prospective randomized controlled trial aims to evaluate whether the timing of ultrasound-guided subcostal transversus abdominis plane (TAP) block combined with rectus sheath block (RSB) affects postoperative pain in patients undergoing laparoscopic cholecystectomy. Participants will be randomly assigned to receive the combined regional blocks either before surgical incision or after completion of surgery. The primary outcome is postoperative pain intensity measured using a numerical rating scale. Secondary outcomes include opioid consumption, incidence of postoperative nausea and vomiting, and other recovery parameters. The results of this study may help optimize the timing of abdominal wall blocks to improve postoperative analgesia and recovery following laparoscopic cholecystectomy.
CONDITIONS
Official Title
Timing of Subcostal TAPB Combined With Rectus Sheath Block for Postoperative Pain After Laparoscopic Cholecystectomy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 to 80 years
- Scheduled for elective laparoscopic cholecystectomy
- Ability to understand the study and provide informed consent
- American Society of Anesthesiologists (ASA) physical status I to III
You will not qualify if you...
- Significant pain unrelated to the target disease interfering with pain assessment
- Known allergy or contraindication to ropivacaine, acetaminophen, nefopam, or pethidine
- Planned single-port laparoscopic cholecystectomy
- American Society of Anesthesiologists (ASA) physical status IV or higher
- Infection or anatomical abnormalities at the abdominal wall injection site
- Major neurological, psychiatric, or systemic diseases affecting pain perception or study evaluation
- Requirement for postoperative mechanical ventilation
- Pregnancy or breastfeeding
- Considered unsuitable by the investigator
- Refusal or inability to provide informed consent
AI-Screening
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Trial Site Locations
Total: 1 location
1
Nowon Eulji University Hospital
Seoul, South Korea, 01830
Actively Recruiting
Research Team
H
Hye-Yeon Cho, MD
CONTACT
S
Soojeong Kang, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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