Actively Recruiting
Tissue Analysis After Tumor Ablation for Liver Metastases Leading to Immediate Retreatment
Led by Memorial Sloan Kettering Cancer Center · Updated on 2026-03-19
200
Participants Needed
1
Research Sites
361 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study will see whether collecting and analyzing needle biopsy samples from cancer liver metastases after a tumor ablation procedure will be able to identify cancer cells that are still alive. The results of these biopsies could help determine the next treatment for your cancer, but the biopsies could cause side effects.
CONDITIONS
Official Title
Tissue Analysis After Tumor Ablation for Liver Metastases Leading to Immediate Retreatment
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of liver metastases from various primary tumors
- Confined liver disease or limited extrahepatic disease stable or controlled for at least 4 months
- Lesions 3 cm or smaller in maximum diameter
- At least one FDG-avid lesion to be treated
- INR less than 1.5
- Platelet count of 50,000 or higher
You will not qualify if you...
- Age under 18 years
- Less than 5 mm distance to a structure (GI or biliary tract) that cannot be protected from ablation injury
- INR greater than 1.5 that cannot be corrected with fresh frozen plasma
- Platelet count under 50,000 that cannot be corrected with transfusion
- More than 3 tumors in the liver
- More than 5 tumors of extrahepatic disease
- Presence of any peritoneal carcinomatosis
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Memorial Sloan Kettering Cancer Center
New York, New York, United States, 10065
Actively Recruiting
Research Team
C
Constantinos Sofocleous, MD, PhD
CONTACT
E
Efsevia Vakiani, MD,PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here