Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06717542

Tissue Analysis of Liver Grafts as a Predictor of Transplant Outcome.

Led by IRCCS Azienda Ospedaliero-Universitaria di Bologna · Updated on 2024-12-05

200

Participants Needed

1

Research Sites

258 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Despite the good clinical results in terms of outcome with the application of HOPE prior to liver transplantation, very little is still known about the phenotypic and molecular changes that occur during perfusion/preservation during HOPE, particularly with regard to endothelial trophism and activation. Delving into these aspects would be very useful to allow personalised perfusion treatments in the future, thus improving the outcome of transplantation.

CONDITIONS

Official Title

Tissue Analysis of Liver Grafts as a Predictor of Transplant Outcome.

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • For liver donors: availability of sufficient tissue for histological, immunohistochemical, and RT-PCR analysis
  • HOPE performed on the liver graft prior to transplantation
  • For liver recipients: availability of sufficient tissue for histological, immunohistochemical, and RT-PCR analysis
  • Age 18 years or older
Not Eligible

You will not qualify if you...

  • None

AI-Screening

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Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

IRCCS Azienda Ospedaliero-Universitaria di Bologna

Bologna, Italy, 40138

Actively Recruiting

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Research Team

F

Francecso Vasuri, MD

CONTACT

D

Deborah Malvi, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

DIAGNOSTIC

Number of Arms

2

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