Actively Recruiting
Tissue Collection for Studies of Lymph Cancer
Led by National Cancer Institute (NCI) · Updated on 2026-05-05
1295
Participants Needed
2
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Background: \- Lab studies help researchers better understand cancer biology. This information may lead to new methods for diagnosing or treating cancer. To develop these studies, researchers want to collect samples from people with cancer or precancer conditions of the lymph system. These conditions include multiple myeloma, different types of lymphoma, and adult leukemia/lymphoma. The samples collected will include blood, urine, bone marrow, and tumor and skin tissue. Objectives: \- To collect tissue samples to study different types of lymph cancer. Eligibility: \- Individuals at least 18 years of age who have a lymphoid cancer or precancer condition. Design: * Participants will be screened with a physical exam and medical history. * Different samples will be collected for study. Blood samples will be collected at the initial testing. More blood samples will be collected at different treatment points. Other liquid samples include urine, bone marrow, and any abnormal fluid. Tumor tissue and skin tissue biopsies will also be collected for study. * Treatment will not be provided as part of this study.
CONDITIONS
Official Title
Tissue Collection for Studies of Lymph Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Confirmed diagnosis of lymphoid malignancy or precursor disease, including multiple myeloma, B-cell and T-cell lymphomas such as diffuse large B-cell lymphoma, Hodgkin's lymphoma, lymphomatoid granulomatosis, or adult T-cell leukemia/lymphoma
- Confirmation of diagnosis by the Laboratory of Pathology, NCI
- ECOG performance status of 0 to 2
- Ability and willingness to sign informed consent (patients enrolling with a legally authorized representative must also be co-enrolled on another study)
- Patients without known lymphoid malignancy who have a planned surgical procedure allowing collection of blood or normal lymph node/tissue for research
- Ability and willingness to sign informed consent for patients without known lymphoid malignancy
You will not qualify if you...
- Pregnant individuals
- Active symptomatic major organ disorders increasing risk of biopsy or apheresis (e.g., ischemic heart disease, recent myocardial infarction, active congestive heart failure, pulmonary dysfunction)
- Active medical or psychological illnesses increasing risk or inability to provide informed consent, per investigator discretion
- For patients without known lymphoid malignancy: active other malignancy (except treated basal or squamous cell carcinoma, stage 1 melanoma, in situ carcinoma, or malignancy treated with curative intent and no evidence of disease for 2 years, at investigator discretion)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
National Institutes of Health Clinical Center
Bethesda, Maryland, United States, 20892
Actively Recruiting
2
University of the West Indies
Kingston, Jamaica
Terminated
Research Team
N
NCIMO Referral Office
CONTACT
C
Christopher J Melani, M.D.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here