Actively Recruiting
Tissue Engineered Cartilage to Repairing Articular Cartilage Defects
Led by The First Affiliated Hospital of Xinxiang Medical College · Updated on 2026-05-04
30
Participants Needed
1
Research Sites
136 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The joint cartilage constructed by combining bone marrow mesenchymal stem cells with three-dimensional materials has achieved the goal of repairing joint cartilage.
CONDITIONS
Official Title
Tissue Engineered Cartilage to Repairing Articular Cartilage Defects
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged 18 to 65 years old
- Mature epiphyseal growth confirmed by imaging
- Localized joint cartilage defects caused by trauma or other reasons
- Injury located on distal weight-bearing surface of femoral condyle of the knee with no more than 4 lesions
- No injury to the cruciate ligaments
- Patients voluntarily sign informed consent and agree to strict postoperative rehabilitation
You will not qualify if you...
- Body mass index greater than 35
- Lower limb alignment with valgus over 10° or varus over 5°
- Multiple ligament injuries
- Heavy smoking, drug abuse, or excessive alcohol consumption
- Open knee surgery within the past 6 months
- Severe joint stiffness or fibrosis
- Allergic reactions to collagen or allergic constitution
- Mental abnormalities
- Unable or unwilling to undergo rehabilitation training
- Primary cardiovascular, lung, endocrine, metabolic diseases, tumors, or AIDS
- Pregnant, lactating, or planning pregnancy during trial
- Other acute or chronic diseases making surgery inappropriate
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The First Affiliated Hospital of Xinxiang Medical College
Xinxiang, Henan, China, 453000
Actively Recruiting
Research Team
W
Wenjie Ren
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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