Actively Recruiting

Age: 18Years - 75Years
FEMALE
NCT06475261

Tissue Oximetry's Measurement in Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy

Led by Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Updated on 2025-03-07

50

Participants Needed

1

Research Sites

61 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Tissue oximetry obtained from peripheral muscle measures the state of tissue oxygenation of various organs and, as already widely described in the literature, can be used to measure the state of kidney's tissue oxygenation. However, there is no evidence in the existing scientific literature on the use of muscle tissue oximetry in patients undergoing cytoreductive surgery for ovarian cancer with hyperthermic intraperitoneal chemotherapy. The primary objective of our study is to evaluate whether there is a correlation between average intraoperative muscle tissue oximetry below 65% (a value which is considered critical in the literature for the resulting cellular damage) and postoperative renal damage in patients undergoing cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for ovarian cancer.

CONDITIONS

Official Title

Tissue Oximetry's Measurement in Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy

Who Can Participate

Age: 18Years - 75Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Female patients classified as American Society Anesthesiologists (ASA) 1 or 2
  • Undergoing cytoreductive surgery for ovarian cancer using laparoscopic or open surgery techniques
  • Receiving hyperthermic intraperitoneal chemotherapy (HIPEC) during surgery
Not Eligible

You will not qualify if you...

  • Younger than 18 years old
  • ASA classification 3 or higher
  • Undergoing cytoreductive surgery without hyperthermic intraperitoneal chemotherapy

AI-Screening

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Trial Site Locations

Total: 1 location

1

Policlinico "A. Gemelli" IRCCS

Rome, Italy

Actively Recruiting

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Research Team

S

Stefano Catarci, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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