Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06782191

TMJ Arthroscopic Lysis and Lavage Compared to Operative Arthroscopy in Disc Displacement With Reduction.

Led by Karolinska Institutet · Updated on 2025-06-29

96

Participants Needed

1

Research Sites

304 weeks

Total Duration

On this page

Sponsors

K

Karolinska Institutet

Lead Sponsor

K

Karolinska University Hospital

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical trial is to compare the intervention arthroscopic lysis and lavage to the intervention operative arthroscopy in treating disabling and painful temporomandibular joint disc displacement with reduction. The main questions it aims to answer are: * Which surgical method that best improves mouth opening capacity, TMJ pain, and TMJ disability? * If any pre- or peri-operative variable/-s could be identified as a predictor for surgical outcome? Researchers will compare arthroscopic lysis and lavage to operative arthroscopy to see if operative arthroscopy works better to treat temporomandibular joint disc displacement. Participants will: * Have one of the two interventions under general anesthesia, not knowing which intervention. * Visit an external clinic for regular checkups at 1, 3, 6, 12, and 24 months after surgery. * Answer three different quality of life surveys at the checkups.

CONDITIONS

Official Title

TMJ Arthroscopic Lysis and Lavage Compared to Operative Arthroscopy in Disc Displacement With Reduction.

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Uni- or bilateral disc displacement with reduction verified by clinical and MRI findings
  • TMJ pain 3 or higher on a numeric rating scale
  • TMJ disability 3 or higher on a numeric rating scale
  • Age 18 years or older
Not Eligible

You will not qualify if you...

  • Prior open temporomandibular joint surgery
  • Diagnosis of rheumatologic joint disease
  • American Society of Anaesthesiologists (ASA) score greater than 3
  • Unable to provide informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Karolinska Institutet

Huddinge, Sweden, 14104

Actively Recruiting

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Research Team

M

Mattias Ulmner, DDS, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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