Actively Recruiting
Transcranial Magnetic Stimulation (TMS) for Complex Regional Pain Syndrome (CRPS)
Led by Stanford University · Updated on 2025-05-13
40
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
Sponsors
S
Stanford University
Lead Sponsor
N
National Institutes of Health (NIH)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are evaluating the use of Transcranial Magnetic Stimulation (TMS) to treat Complex Regional Pain Syndrome (CRPS), a condition causing pain and related cognitive, emotional, and physical symptoms. The study aims to compare the effects of active TMS treatment to a sham (placebo) treatment to see if TMS can reduce pain and improve symptoms. Participants will be monitored to assess both the effectiveness and safety of the treatment over time.
CONDITIONS
Brief Title
TMS for Complex Regional Pain Syndrome
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 to 70 years
- Diagnosis of Complex Regional Pain Syndrome (CRPS) for at least 3 months
- Average pain level meets study entry criteria on a Numerical Rating Scale
- Ability to perform study tasks and procedures
You will not qualify if you...
- Contraindications for MRI such as metal implants or claustrophobia
- Contraindications for TMS, including metal implants near stimulation site
- History of epilepsy
- Psychological or psychiatric disorders interfering with study procedures
- Neurologic illnesses affecting brain integrity
- Current medical conditions or medications interfering with procedures or data
- Pregnant or planning pregnancy
- Ongoing legal actions or disability claims
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 2 days
Participants receive Transcranial Magnetic Stimulation (TMS) once daily for two days either in the target area or in a non-target area depending on group assignment.
2 visits (in-person, daily)
Duration - Up to 6 months
Participants are monitored for changes in pain and duration of pain relief for up to 6 months after treatment.
1 follow-up visit approximately 1 week after treatment and additional contact as needed up to 6 months
Trial Site Locations
Total: 1 location
1
Stanford Pain Management Center
Redwood City, California, United States, 94043
Actively Recruiting
Research Team
O
Omar Altirkawi
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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