Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06425146

Tobacco, Alcohol and Cancerization of the Oral Mucosa (TACO)

Led by Centre Leon Berard · Updated on 2024-08-22

30

Participants Needed

1

Research Sites

57 weeks

Total Duration

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AI-Summary

What this Trial Is About

The goal of this project is to describe somatic mutations of healthy oral mucosa from patients with oral squamous cell carcinoma (OSCC).

CONDITIONS

Official Title

Tobacco, Alcohol and Cancerization of the Oral Mucosa (TACO)

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Male or female aged 18 years or older at the date of signature of the informed consent to participate.
  • Patient with histological diagnosis of epidermoid carcinomas of the oral cavity; all grades are eligible.
  • Patient naive of any systemic anti-cancer treatment (radio- or chemotherapy).
  • Patient able to understand, sign and date informed consent before the start of any study protocol procedure.
  • Patient affiliated or covered by a medical insurance
Not Eligible

You will not qualify if you...

  • Patients at high risk of bleeding, such as those on anticoagulant or antiplatelet treatment, with clotting disorders or recent severe bleeding within two weeks prior to inclusion.
  • Patient with lesions on the cheek mucosa opposite to the cancer area preventing painless removal of healthy mucosa.
  • Patient who had surgery for their oral cavity epidermoid carcinoma more than 6 months ago.
  • Patient who uses cannabis.
  • Patient with another active tumor or HPV-positive tumors.
  • Patient under guardianship, curatorship, or legal protection.
  • Pregnant and/or nursing patient.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Centre Léon Bérard

Lyon, France, 69008

Actively Recruiting

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Research Team

P

Philippe Zrounba, M.D.

CONTACT

P

Pierre Martinez, Ph.D.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

PREVENTION

Number of Arms

1

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