Actively Recruiting
Tolerance to an Artisanal Bread in a Population Intolerant of the Conventional Bread and Study of Associated Markers
Led by Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement · Updated on 2026-05-05
40
Participants Needed
2
Research Sites
69 weeks
Total Duration
On this page
Sponsors
I
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Lead Sponsor
U
UMR 914 PNCA - AgroParisTech, INRA, Université Paris-Saclay
Collaborating Sponsor
AI-Summary
What this Trial Is About
The objective of this study is to evaluate the effect of consuming an "artisanal" bread for 15 days on gastrointestinal symptoms in individuals intolerant to "conventional" bread. "Conventional bread" refers to bread made with refined wheat flour (ash = 0.55% of dry matter), containing gluten, and leavened with baker's yeast (Saccharomyces cerevisiae). "Artisanal bread" refers to bread made with whole wheat flour (ash = 1.50% of dry matter) from an ancient durum wheat variety (Russello) and leavened with sourdough.
CONDITIONS
Official Title
Tolerance to an Artisanal Bread in a Population Intolerant of the Conventional Bread and Study of Associated Markers
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Normal weight (BMI between 18 and 25 kg/m²)
- Male or female
- Age between 18 and 65 years
- Adults reporting intolerance to conventional bread
- No diagnosis of celiac disease
- Affiliated with a social security scheme
- Provided free, informed, and express consent
You will not qualify if you...
- Under legal guardianship, tutorship, or curatorship
- Diagnosis of eating disorders such as anorexia, bulimia, or binge eating
- Known food allergies
- Pregnant or potentially pregnant women
- Breastfeeding women
- Alcohol abuse exceeding 2 drinks per day
- Untreated hypertension, uncontrolled diabetes, or diseases affecting the digestive tract (excluding functional disorders), liver, kidneys, or severe heart disease
- Participation in another clinical study within the last three months
- Absence of express consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Centre de Recherche sur Volontaires
Bobigny, France, 93000
Actively Recruiting
2
Centre de Recherche sur Volontaires (CRV)
Bobigny, Île-de-France Region, France, 93000
Not Yet Recruiting
Research Team
F
Fabien Wuestenberghs
CONTACT
C
Claire Gaudichon
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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