Actively Recruiting
Tonsillectomy Versus Tonsillotomy in the Treatment of Recurrent Acute Tonsillitis
Led by Tejs Ehlers Klug · Updated on 2024-12-19
250
Participants Needed
2
Research Sites
269 weeks
Total Duration
On this page
Sponsors
T
Tejs Ehlers Klug
Lead Sponsor
U
University of Aarhus
Collaborating Sponsor
AI-Summary
What this Trial Is About
Background: recurrent acute tonsillitis (RT) is a frequent condition affecting teenagers and adults. Patients suffer from recurring throat symptoms, fever and impaired quality of life (QOL). Tonsillectomy (TE) is the only well-known treatment, but studies indicate that tonsillotomy (TO) is associated with less morbidity (eg. pain and bleeding) and equal efficiency (e.g. reduced number of sore throat episodes and improved QOL). The investigator aim to clarify whether TO is a non-inferior alternative to TE. Methods: inclusion and randomization of 250 adult RT patients for TE or TO with a 12 month follow up. Comparisons will be made between groups, and outcome measures includes number of sore throat episodes, QOL and postoperative pain. Discussion: the study has the potential to improve the treatment of a prevalent disease by enhancing knowledge of an alternative procedure (TO) associated with less discomfort and risk than the current standard procedure (TE) and a presumably low risk of insufficiency.
CONDITIONS
Official Title
Tonsillectomy Versus Tonsillotomy in the Treatment of Recurrent Acute Tonsillitis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 15 years or older with recurrent tonsillitis, defined as at least five episodes in one year or at least three episodes per year for two years
- Ability to understand Danish both orally and in writing
You will not qualify if you...
- Previous tonsillectomy or tonsillotomy
- Suspected cancer in the tonsils
- History of cancer in the mouth, throat, or voice box
- Previous radiation therapy to the head or neck
- Bleeding disorders or use of blood-thinning medications
AI-Screening
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Trial Site Locations
Total: 2 locations
1
Aalborg University Hospital
Aalborg, Denmark, 9000
Actively Recruiting
2
Aarhus University Hospital
Aarhus, Denmark, 8200
Actively Recruiting
Research Team
H
Hannah Inez Houborg, MD
CONTACT
T
Tejs Ehlers Klug, MD, DMSc
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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