Actively Recruiting

Phase Not Applicable
Age: 18Years - 99Years
All Genders
NCT06406530

Topical Application of PRF Before Radiation Therapy

Led by University of Giessen · Updated on 2025-04-11

34

Participants Needed

1

Research Sites

91 weeks

Total Duration

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AI-Summary

What this Trial Is About

The primary goal of this study is to observe whether PRP promotes the wound healing before a radiation therapy or not, compared to the natural healing of a tooth extraction socket. Secondary aim is to monitore the effect on the pain perception.

CONDITIONS

Official Title

Topical Application of PRF Before Radiation Therapy

Who Can Participate

Age: 18Years - 99Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with head and neck cancer planned for radiation therapy
  • Require extraction of two or more teeth on both sides of the jaw
  • Teeth to be extracted must be similar in size (e.g., molar and molar)
  • Tooth extractions must be atraumatic without flap surgery
  • Participants must be 18 years of age or older
Not Eligible

You will not qualify if you...

  • Previous radiation therapy in the head and neck area
  • Current or past treatment with bisphosphonates or similar biologic drugs
  • Pregnancy or breastfeeding

AI-Screening

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Trial Site Locations

Total: 1 location

1

University of Giessen

Giessen, Hesse, Germany

Actively Recruiting

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Research Team

S

Sameh Attia, DDS, MSc

CONTACT

J

Jan Nuernberg, DDS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

2

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Topical Application of PRF Before Radiation Therapy | DecenTrialz