Actively Recruiting
Topical Chlorhexidine Spray for the Prevention of Acute Radiation Dermatitis in Patients With Nasopharyngeal Carcinoma:
Led by Jiangxi Provincial Cancer Hospital · Updated on 2026-04-30
148
Participants Needed
1
Research Sites
78 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study investigated the effects of topical chlorhexidine spray on the incidence, severity, and quality of life during radiotherapy in nasopharyngeal carcinoma patients.
CONDITIONS
Official Title
Topical Chlorhexidine Spray for the Prevention of Acute Radiation Dermatitis in Patients With Nasopharyngeal Carcinoma:
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Histologically or cytologically confirmed nasopharyngeal carcinoma
- Clinical stage II-III disease with N651, according to the UICC/AJCC 9th edition
- Planned to receive first-course definitive chemoradiotherapy with a total radiotherapy dose of 60-70 Gy
- Able to communicate and complete study assessments
- Willing to participate and able to provide written informed consent
- Eligible based on baseline assessments performed before chemoradiotherapy
You will not qualify if you...
- History of or current psychiatric disorder, cognitive impairment, or other severe organic disease
- Presence of another concomitant malignancy
- Receipt of any other prophylactic intervention for radiation dermatitis
- Pre-existing skin disease before chemoradiotherapy
- Known hypersensitivity or allergy to chlorhexidine
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Jiangxi Cancer Hospital
Nanchang, Jiangxi, China, 330029
Actively Recruiting
Research Team
T
Tianzhu Lu, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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