Actively Recruiting
Topical Cryotherapy and Keloid/Hypertrophic Scars
Led by Sonal Choudhary · Updated on 2026-05-06
30
Participants Needed
1
Research Sites
65 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to determine whether the application of brief topical cryotherapy immediately before intralesional corticosteroid injections can reduce pain and injection resistance during routine treatment of keloid and hypertrophic scars in adult patients. The main questions it aims to answer are: Does topical cryotherapy applied before intralesional triamcinolone injection impact pain perceptions for participants with keloids or hypertrophic scars? Does topical cryotherapy affect provider-assessed injection resistance compared with standard injection alone? Researchers will split the keloid/hypertrophic scar into two halves. One half will be treated with cryotherapy followed by steroid injection, while the other half will be treated with steroid injection alone to evaluate differences in pain perception and injection resistance. Participants will rate pain after each injection using a 10-point numeric pain scale. Clinicians will rate the resistance after each injection using a 10-point numeric scale.
CONDITIONS
Official Title
Topical Cryotherapy and Keloid/Hypertrophic Scars
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults (18 years or older) with keloids or hypertrophic scars already scheduled for intralesional triamcinolone treatment
- At least one keloid or hypertrophic scar with two comparable regions of 2 cm or more suitable for split-treatment
- Able to provide informed consent and complete pain assessments in English
You will not qualify if you...
- Keloid or hypertrophic scar located on the face, except earlobes, excluded for cosmetic reasons
- Prior treatment to the study-selected keloid or hypertrophic scar based on self-report
- Inability to complete study assessments due to cognitive or language barriers
AI-Screening
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Trial Site Locations
Total: 1 location
1
University of Pittsburgh
Pittsburgh, Pennsylvania, United States, 15213-3427
Actively Recruiting
Research Team
S
Sonal Choudhary, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
1
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