Actively Recruiting
Topical Estrogen: Brief Intervention to Improve Postoperative Experience for Transgender Men Undergoing Hysterectomy
Led by Women and Infants Hospital of Rhode Island · Updated on 2025-05-13
48
Participants Needed
1
Research Sites
82 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to determine if applying a single dose of topical estrogen cream in the operating room at the end of your hysterectomy (removal of uterus and cervix) improves the postoperative experience with bleeding and potential symptoms of dysphoria (a feeling of discomfort or distress). Topical estrogen cream is sometimes used if patients have increased risk of bleeding with surgery but is not currently utilized in a consistent way. This study aims to answer the question of whether this is a helpful treatment and should be included in standard postoperative care.
CONDITIONS
Official Title
Topical Estrogen: Brief Intervention to Improve Postoperative Experience for Transgender Men Undergoing Hysterectomy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Gender diverse/transgender men
- Age 18 or older
- On testosterone therapy for at least 6 months with plan for gender-affirming hysterectomy
- Stable physical and mental health
- No contraindications to estrogen therapy
- Proficient in English or Spanish
- Access to a device to receive text messages for study follow-up
- Agree to allow medical data use for research purposes
You will not qualify if you...
- Under age 18
- Not on testosterone therapy for at least 6 months before planned hysterectomy
- Known allergy to topical estrogen
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Women & Infants Hospital
Providence, Rhode Island, United States, 02905
Actively Recruiting
Research Team
B
Beth Cronin, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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