Actively Recruiting
Topical Imiquimod Treatment of Oral Dysplasia
Led by University of Southern California · Updated on 2026-03-04
20
Participants Needed
1
Research Sites
104 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to determine the effectiveness of imiquimod in treating oral dysplasia in adult patients. Imiquimod 5% cream could be a safe and practical treatment for oral epithelial dysplasia (a precancerous change in the mouth). The main questions it aims to answer are: 1. Does imiquimod help to make the lesions smaller and make the abnormal cell changes less severe? 2. How can we make this treatment safer and more feasible? Participants will apply topical imiquimod cream to treat the oral dysplasia and receive two follow-up biopsies after the treatment.
CONDITIONS
Official Title
Topical Imiquimod Treatment of Oral Dysplasia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Biopsy-proven diagnosis of oral epithelial dysplasia
- Not eligible for or unwilling to have surgical or laser therapy
- Age over 18 years
- Agrees to participate and completes informed consent
You will not qualify if you...
- Oral leukoplakia requiring surgical removal
- Immunocompromised status
- Under 18 years old
- Refusal or failure to complete informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
OralCare PreCancer and Pain Clinic
Los Angeles, California, United States, 90089
Actively Recruiting
Research Team
A
Anette Vistoso Monreal
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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