Actively Recruiting

Phase 1
Age: 18Years +
All Genders
NCT05206877

Topical Insulin for Glaucoma

Led by Stanford University · Updated on 2025-11-25

52

Participants Needed

1

Research Sites

247 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this Phase 1 trial is to determine the safety over 1-2 months of topic sterile human recombinant insulin on subjects with optic neuropathies (glaucoma, ischecmic optic neuropathy, and optic disc drusen).

CONDITIONS

Official Title

Topical Insulin for Glaucoma

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Capable to provide informed consent
  • Diagnosis of optic neuropathy including glaucoma, NAION, or optic disc drusen
  • Only one eye per patient will be selected as the study eye, chosen by worse acuity or visual field if both eyes qualify
Not Eligible

You will not qualify if you...

  • Pregnant or breastfeeding women
  • Presence of other ocular diseases causing severe vision loss such as retinopathy, maculopathy, severe uveitis, or keratopathy
  • Diagnosis of glucose intolerance or type 1 or type 2 diabetes mellitus
  • Inability to perform reliable visual field testing
  • Unable to provide informed consent
  • Unable to complete required tests and follow-ups for the study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Byers Eye Institute at Stanford University

Palo Alto, California, United States, 94303

Actively Recruiting

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Research Team

M

Mariana Nunez, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

7

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