Actively Recruiting

Phase 4
Age: 18Years +
All Genders
NCT05303805

Topical Sevoflurane for Treatment of Chronic Leg Ulcers

Led by Charles University, Czech Republic · Updated on 2024-08-27

50

Participants Needed

1

Research Sites

247 weeks

Total Duration

On this page

Sponsors

C

Charles University, Czech Republic

Lead Sponsor

F

Faculty Hospital Kralovske Vinohrady

Collaborating Sponsor

AI-Summary

What this Trial Is About

Patients with painful non-healing leg ulcer will be enrolled in the clinical single-blinded randomized study. The active treatment group will have sevoflurane applied at approximately 1 ml/cm2 at the start of wound treatment, the control group will only have a standard rinse solution with Cyteal TM (Pierre Fabre Medicament, France). Further treatment will then be carried out in the standard manner. The duration of the study will be 5 days; if the defect heals earlier, it will be terminated early. Exclusion criteria: allergy to sevoflurane, inability to understand the questionnaire Parameters to be monitored will be pain intensity, microbial colonization, appearance and size of the defect

CONDITIONS

Official Title

Topical Sevoflurane for Treatment of Chronic Leg Ulcers

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with painful (pain intensity on the numerical scale NRS 0-10 is NRS>4) non- healing tibial venous ulcers
Not Eligible

You will not qualify if you...

  • Allergy to sevoflurane
  • Inability to understand the pain-intensity questionnaire

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Faculty Hospital Kralovske Vinohrady

Prague, Czechia, 100 00

Actively Recruiting

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Research Team

J

Jiri Malek, M.D.

CONTACT

J

Jiri Malek, M.D.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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