Actively Recruiting

Phase 3
Age: 18Years +
All Genders
NCT05816226

Topical Treatment for TMJ Arthralgia

Led by University of the Pacific · Updated on 2024-12-11

90

Participants Needed

1

Research Sites

147 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this clinical trial is to evaluate the efficacy of topical 2.5% hydrocortisone in TMJ arthralgia. The main questions it aims to answer are: * How does pain reduction compare? * How does improvement in jaw function limitation compare? * How do side effects compare? Participants will * On day 1 be examined and report their pain level and jaw function limitation * On days 1-21, apply their cream four times a day * On day 21, report their pain level, jaw function limitation, compliance with instructions, and side effects. Researchers will compare topical 2.5% hydrocortisone and topical 1% diclofenac to see if efficacy and side effects differ.

CONDITIONS

Official Title

Topical Treatment for TMJ Arthralgia

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Arthralgia of at least one TMJ lasting at least 3 days
Not Eligible

You will not qualify if you...

  • Presence of systemic pain conditions
  • Past adverse reaction to steroids
  • Current steroid use
  • Steroid use within the past several months
  • Use of muscle relaxants during the study
  • Use of a new night guard during the study or within 1 month before starting the study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Arthur A. Dugoni School of Dentistry, University of the Pacific

San Francisco, California, United States, 94103

Actively Recruiting

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Research Team

A

Andrew Young, DDS, MSD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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