Actively Recruiting
Total-body Glucose Utilization in Obesity
Led by Turku University Hospital · Updated on 2024-12-18
60
Participants Needed
1
Research Sites
96 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
There are three goals for this study. One is to investigate how different emotions and exposure to cold affect blood flow in the body. The second aim is to study how insulin affects blood flow and tissue glucose uptake, and to study whether this effect is altered in obesity. Last, the study focuses on establishing the lowest dose of a PET radiotracer, oxygen-15 labelled water, that can be used in clinical studies with a new whole-body PET scanner.
CONDITIONS
Official Title
Total-body Glucose Utilization in Obesity
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 20 and 60 years
- Body mass index (BMI) either 18.5-25 kg/m2 or above 30 kg/m2
- Women of childbearing age must be using hormonal contraception
You will not qualify if you...
- History of obesity or type 2 diabetes in participants with normal weight
- Current or previous use of GLP-1 agonists or insulin in participants with obesity
- History of eating disorders
- Smoking, use of narcotics, or excessive alcohol use
- Previous participation in PET studies
- Significant prior exposure to radiation
- Claustrophobia
- Active plans to conceive for both sexes
- Any condition that may pose a safety risk, interfere with study procedures, or affect results according to the investigator
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Turku PET Centre
Turku, Finland, 20521
Actively Recruiting
Research Team
A
Aino Latva-Rasku, MD, PhD
CONTACT
S
Sanna Himanen, RN
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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