Actively Recruiting
Total Intravenous Anesthesia (TIVA)/Sevoflurane Initiated Intravenous Anesthesia (SIIVA) in Pediatric Patients
Led by Wake Forest University Health Sciences · Updated on 2025-12-18
600
Participants Needed
2
Research Sites
257 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Because Propofol is the primary "anesthetic agent," and inhalational agents remain in trace quantities at the end of the procedure Sevoflurane initiated intravenous anesthesia (SIIVA) or not present at all Total intravenous anesthesia (TIVA) it is likely that different criteria may be predictive of extubation success in these patients compared to inhalational anesthesia.
CONDITIONS
Official Title
Total Intravenous Anesthesia (TIVA)/Sevoflurane Initiated Intravenous Anesthesia (SIIVA) in Pediatric Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Pediatric patients younger than 10 years of age
- Undergoing elective or emergency surgery with planned airway instrumentation using an endotracheal tube
- Receiving general anesthesia with planned Sevoflurane Initiated Intravenous Anesthesia (SIIVA) or Total Intravenous Anesthesia (TIVA)
- Having end tidal Sevoflurane concentration less than 0.1% at the time of emergence and extubation after sevoflurane induction to place IV
You will not qualify if you...
- History of home oxygen use or ventilator dependence
- Presence of cyanotic congenital heart disease
- Undergoing anesthesia for imaging procedures only
- Planned use of supraglottic airway instead of endotracheal tube
- Anesthesia duration less than 30 minutes
- Receiving Monitored Anesthesia Care instead of general anesthesia
- Contraindication to Propofol use, such as mitochondrial myopathy
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 2 locations
1
Atrium Health Wake Forest Baptist
Winston-Salem, North Carolina, United States, 27157
Actively Recruiting
2
Perth Children's Hospital
Perth, Australia
Not Yet Recruiting
Research Team
W
Wes Templeton, MD
CONTACT
L
Lynne Harris, BSN
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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