Actively Recruiting
Total Periarticular Infiltration Vs Posterior Periarticular Infiltration Plus PENG Block for Hip Analgesia
Led by University of Chile · Updated on 2025-01-17
74
Participants Needed
1
Research Sites
105 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
In a recent study, direct periarticular local anesthetic infiltration (PAI) showed a greater incidence of early quadriceps weakness (33% at 3 hours and 13% at 6 hours) than pericapsular nerve group block (PENGB) in total hip arthroplasty (THA) but, in turn, demonstrated a statistically significant better pain control. Additionally, PENGB could not completely circumvent motor compromise either, particularly at 3 hours (20% incidence), probably secondary to an injectate migration towards the femoral nerve. Posteriorly to this publication, a cadaveric trial looking into the maximum effective volume that spared the femoral nerve resulted in 13.2 mL. This newer evidence led to the design of a strategy that combines both interventions, aiming to obtain the best of them and have a solid alternative for those cases where very early mobilization is pursued. Thus, it is hypothesized that posterior PAI added to a low-volume PENGB (10mL) represents a superior alternative to PAI in terms of strength preservation and provides effective analgesia during the first 24 postoperative hours after THA.
CONDITIONS
Official Title
Total Periarticular Infiltration Vs Posterior Periarticular Infiltration Plus PENG Block for Hip Analgesia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- American Society of Anesthesiologists classification 1-3
- Body mass index between 20 and 35 (kg/m2)
You will not qualify if you...
- Adults who are unable to give their own consent
- Pre-existing neuropathy (assessed by history and physical examination)
- Coagulopathy (assessed by history, physical examination, and possibly blood tests)
- Renal failure (assessed by history, physical examination, and possibly blood tests)
- Hepatic failure (assessed by history, physical examination, and possibly blood tests)
- Allergy to local anesthetics or morphine
- Pregnancy
- Prior surgery in the inguinal area on the surgical side
- Chronic pain syndromes requiring opioid use at home
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Hospital Clínico Universidad de Chile
Santiago, Santiago Metropolitan, Chile, 8380456
Actively Recruiting
Research Team
D
Daniela Bravo, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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