Comparing Manual Total Knee Replacement and Robotic-Assisted Partial Knee Replacement for Knee Osteoarthritis in Adults Aged 50 to 75

What this Trial Is About

This research compares functional outcomes and costs between two types of knee replacement surgeries for patients with end-stage medial compartment osteoarthritis of the knee. It focuses on manual total knee arthroplasty mTKA versus robotic-assisted unicompartmental knee arthroplasty rUKA. The study aims to evaluate whether the newer robotic-assisted technique improves early knee function while addressing concerns about revision rates seen with traditional unicompartmental procedures. Participants will receive either a conventional manual total knee replacement using a Triathlon Stryker implant or a robotic-assisted partial knee replacement with the MAKO system. The manual group undergoes bone cuts using traditional tools, while the robotic group uses a robotic arm guided by a CT-based 3D model for precise bone preparation and implant placement. Both surgeries aim to balance the knee through a range of motion. During the study, participants will be assessed on knee function and satisfaction using measures like the Oxford knee score, Forgotten Joint Score, range of motion, and patient questionnaires at multiple time points up to 12 months. Researchers will also monitor cost-effectiveness and knee stability. The trial is randomized and double-blinded, with follow-up evaluations extending to one year after surgery.

Total Versus Robotic Assisted Unicompartmental Knee Replacement