Actively Recruiting
TOward a comPrehensive Supportive Care Intervention for Older Men With Metastatic Prostate Cancer
Led by University Health Network, Toronto · Updated on 2025-07-03
168
Participants Needed
3
Research Sites
196 weeks
Total Duration
On this page
Sponsors
U
University Health Network, Toronto
Lead Sponsor
R
Rising Tide Foundation
Collaborating Sponsor
AI-Summary
What this Trial Is About
TOPCOP3 is a pilot factorial RCT of geriatric assessment and management, remote symptom monitoring, both interventions or neither, accompanied by an embedded process evaluation. This design is widely used to guide the evaluation of complex interventions and provides important data to aid design of larger RCTs. The trial itself falls within pilot trial goals including obtaining variance estimates for outcomes, assessment of recruitment potential, and understanding implementation issues vital to designing a larger trial. The investigators have clear feasibility objectives and an analytic plan as well as criteria to determine success and strong support from cancer advocacy and policy groups.
CONDITIONS
Official Title
TOward a comPrehensive Supportive Care Intervention for Older Men With Metastatic Prostate Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Starting an androgen receptor axis-targeted therapy (ARAT) or started ARAT within 2 weeks prior to being approached or switching ARATs due to progression or toxicity
- Diagnosed with metastatic prostate cancer (castration-sensitive or resistant) or non-metastatic castration-resistant prostate cancer
- At least 65 years old
- Able to provide written informed consent
- Has a working telephone
You will not qualify if you...
- Unable to speak English
- Major neuropsychiatric abnormalities such as severe depression or moderate-severe dementia
- Life expectancy less than 3 months as estimated by the oncologist
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
St. Michael's hospital
Toronto, Ontario, Canada, M5B 1W8
Actively Recruiting
2
University Health Network - Princess Margaret Cancer Centre
Toronto, Ontario, Canada, M5G 2C1
Actively Recruiting
3
Sunnybrook Health Sciences Centre
Toronto, Ontario, Canada
Actively Recruiting
Research Team
S
Shabbir Alibhai, MD
CONTACT
S
Soha Abdallah, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
FACTORIAL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
4
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