Actively Recruiting

Age: 5Years - 25Years
All Genders
NCT06998134

Toward Ubiquitous Lower Limb Exoskeleton Use in Children and Young Adults

Led by National Institutes of Health Clinical Center (CC) · Updated on 2026-05-14

23

Participants Needed

1

Research Sites

117 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

People with cerebral palsy (CP), muscular dystrophy (MD), spina bifida, or spinal cord injury often have muscle weakness, and problems moving their arms and legs. The NIH designed a new brace device, called an exoskeleton, that is worn on the legs and helps people walk. This study is investigating new ways the exoskeleton can be used in multiple settings while performing different walking or movement tasks, which we call ubiquitous use. For example, we will ask you to walk on a treadmill at different speeds, walk up and down a ramp, or walk through an obstacle course. Optionally, the exoskeletons may also use functional electrical stimulation (FES), a system that sends electrical pulses to the muscle to help it move the limb.

CONDITIONS

Official Title

Toward Ubiquitous Lower Limb Exoskeleton Use in Children and Young Adults

Who Can Participate

Age: 5Years - 25Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Signed informed consent and assent forms are required for screening and participation
  • Willingness and ability to comply with all study procedures and availability for the study duration
  • Age between 5 and 25 years old
  • Diagnosis of cerebral palsy, muscular dystrophy, spina bifida, spinal cord injury, or no gait pathology
  • Knee joint range of motion of at least 25 degrees in the sagittal plane with hip extended
  • Ankle joint range of motion of at least 15 degrees in the sagittal plane with foot in neutral position
  • Ability to walk at least 10 feet without stopping, with or without walking aid
Not Eligible

You will not qualify if you...

  • Any neurological, musculoskeletal, or cardiorespiratory condition other than the specified diagnoses that affects walking with the exoskeleton
  • History of uncontrolled seizures within the past year
  • Pregnancy based on self-report
  • Adults unable to provide consent at screening

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

National Institutes of Health Clinical Center

Bethesda, Maryland, United States, 20892

Actively Recruiting

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Research Team

J

Jesse H Matsubara

CONTACT

T

Thomas C Bulea, Ph.D.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

4

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