Towards a Sex-specific Female Enhanced Recovery After Cardiac Surgery Pathway: An Observational Registration and Evaluation of Characteristics and Perioperative Management of Cardiac Surgery Patients

What this Trial Is About

This research aims to evaluate differences between men and women undergoing cardiac surgery by examining various perioperative factors. These include body weight, body surface area, medical history, pharmacokinetics, transfusion, coagulation, cardiopulmonary bypass-related factors, cardiac function, inotropic needs, risk and outcome scores, as well as morbidity and mortality at multiple time points up to 10 years. The study is observational and collects data retrospectively and prospectively to better understand sex-specific outcomes after cardiac surgery. The study collects retrospective data from the Netherlands Heart Registry and electronic patient files, covering patients who had cardiac surgery from January 2016 until the study's start. It then continues prospectively with patients undergoing cardiac surgery from the study start until around 2032. No experimental treatments are given; instead, data is gathered from standard care and supplemented with questionnaires sent to patients one, five, and ten years after surgery to assess quality of life. Participants will be followed through registry data and questionnaires to monitor outcomes such as morbidity, mortality, survival, and health-related quality of life at various intervals after surgery. The primary outcome focuses on events up to 30 days post-surgery, with longer-term follow-ups at 90 days, one year, five years, and ten years. No additional interventions are performed beyond routine care and questionnaires, allowing for comprehensive observation of patient experiences and outcomes over time.

Towards a Sex-specific "Female Enhanced Recovery After Cardiac Surgery'' (F-ERAS) Pathway: