Actively Recruiting

Age: 18Years +
All Genders
NCT06580106

Toxicity Genetic Determinants and Response to Azacitidine and Venetoclax in AML

Led by Wake Forest University Health Sciences · Updated on 2026-02-02

50

Participants Needed

2

Research Sites

246 weeks

Total Duration

On this page

Sponsors

W

Wake Forest University Health Sciences

Lead Sponsor

A

Atrium Health Levine Cancer Institute

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this research is to see how certain genetic variations relate to side effects and outcomes experienced while receiving treatment with azacitidine and venetoclax.

CONDITIONS

Official Title

Toxicity Genetic Determinants and Response to Azacitidine and Venetoclax in AML

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Provide written informed consent and HIPAA authorization.
  • Be 18 years of age or older at enrollment.
  • Have a confirmed diagnosis of acute myeloid leukemia (AML).
  • Plan to receive initial treatment with azacitidine and venetoclax.
  • Be able to read and understand English or Spanish.
  • Be able to understand and comply with study procedures for the entire study duration as judged by the investigator.
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

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Trial Site Locations

Total: 2 locations

1

Levine Cancer Institute

Charlotte, North Carolina, United States, 28204

Actively Recruiting

2

Wake Forest Baptist Comprehensive Cancer Center

Winston-Salem, North Carolina, United States, 27157

Actively Recruiting

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Research Team

C

Courtney Schepel

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Toxicity Genetic Determinants and Response to Azacitidine and Venetoclax in AML | DecenTrialz