Actively Recruiting

Phase Not Applicable
Age: 45Years - 80Years
All Genders
NCT05163951

Trabeculectomy Versus Peripheral Iridectomy Plus Goniotomy in Advanced PACG

Led by Sun Yat-sen University · Updated on 2022-06-14

88

Participants Needed

1

Research Sites

233 weeks

Total Duration

On this page

Sponsors

S

Sun Yat-sen University

Lead Sponsor

T

The Second Affiliated Hospital of Harbin Medical University

Collaborating Sponsor

AI-Summary

What this Trial Is About

A multicenter, parallel, open, non-inferior randomized controlled trial is conducted to compare the effectiveness and safety of trabeculectomy and peripheral iridectomy plus goniotomy (TVG) in the treatment of advanced primary angle closure glaucoma with no or mild cataracts.

CONDITIONS

Official Title

Trabeculectomy Versus Peripheral Iridectomy Plus Goniotomy in Advanced PACG

Who Can Participate

Age: 45Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 45 and 80 years
  • Diagnosed with advanced primary angle closure glaucoma meeting specific eye pressure, optic nerve, and visual field criteria
  • No or mild cataracts with uncorrected visual acuity of at least 0.63
  • Axial eye length of 20 mm or more
Not Eligible

You will not qualify if you...

  • History of eye surgery or trauma
  • Presence of retinal disease affecting eye measurements or other types of glaucoma
  • Best-corrected visual acuity below 0.01 in the non-study eye (monophthalmia)
  • International Standardized Ratio above 3.0 for patients on warfarin or anticoagulants before surgery
  • Serious systemic diseases
  • Pregnant or breastfeeding women

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Zhongshan Ophthalmic Center, Sun Yat-sen University

Guangzhou, Guangdong, China, 510060

Actively Recruiting

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Research Team

X

Xiulan Zhang, MD. PhD

CONTACT

X

Xinbo Gao, MD. PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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