Actively Recruiting

Phase 2
Age: 18Years - 65Years
All Genders
NCT07282483

Traditional Chinese Medicine Oral Liquids and Mouthwashes for Radiation-induced Oral Mucositis in Head and Neck Cancer Patients

Led by West China Hospital · Updated on 2026-03-25

118

Participants Needed

1

Research Sites

32 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Evaluate the efficacy and safety of traditional Chinese medicine oral liquid and mouthwash in the treatment of radiotherapy induced oral mucositis in patients with head and neck malignancies

CONDITIONS

Official Title

Traditional Chinese Medicine Oral Liquids and Mouthwashes for Radiation-induced Oral Mucositis in Head and Neck Cancer Patients

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients pathologically diagnosed with non-metastatic head and neck malignant tumors
  • Age range: 18 to 65 years old (including 18 and 65 years old)
  • Eastern Cooperative Oncology Group performance status of 2
  • Radiotherapy or concurrent chemoradiotherapy is required
  • The main organ functions well
  • Sign informed consent.
Not Eligible

You will not qualify if you...

  • Allergic constitution (such as those known to be allergic to two or more drugs)
  • Patients who plan to use drugs that can cause or worsen oral mucosal inflammation (such as anti EGFR monoclonal antibodies, immune checkpoint inhibitors, etc.) after the start of radiotherapy
  • Use of antibiotics, antifungal drugs, or antimicrobial mouthwash within 1 month of the study
  • Poor oral hygiene and/or severe periodontal diseases
  • History of head and neck radiotherapy
  • Deemed unsuitable for the study by the investigators (concomitant with any other severe diseases)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

West China Hospital

Chengdu, Sichuan, China, 610041

Actively Recruiting

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Research Team

X

Xingchen Peng, Professor

CONTACT

J

Jiayi Yu, Doctor

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Traditional Chinese Medicine Oral Liquids and Mouthwashes for Radiation-induced Oral Mucositis in Head and Neck Cancer Patients | DecenTrialz