Actively Recruiting
Train Your Brain Fitness SC: An Exercise Intervention for People With Cognitive Impairments
Led by University of South Carolina · Updated on 2026-06-01
50
Participants Needed
2
Research Sites
2 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating a twice-weekly, moderate intensity exercise and coaching program for adults with mild to moderate cognitive impairment living in South Carolina. The study aims to determine whether the program is practical, acceptable, and enjoyable, and whether participants show changes in endurance, mobility, cognitive function, and perception of cognition at 3, 6, 9, and 12 months. The study is led by the University of South Carolina and focuses on maintaining or improving cognitive and physical abilities. Participants join either an in-person exercise group in Columbia, SC, or a distance exercise group in Sumter, SC. The in-person group attends twice weekly sessions at a fitness center with real-time coaching and feedback, including endurance, strength, balance, and mobility exercises. The distance group receives personalized exercise plans, attends up to seven initial visits with a fitness trainer, and completes the rest of the exercise sessions independently, logging their activity and intensity with support from coaches via phone, text, or email. Throughout the study, participants wear heart rate monitors and have their exercise sessions tracked for intensity, duration, and adherence. Assessments of cognitive function, endurance, mobility, balance, grip strength, and perception of cognition are conducted at baseline and at 3, 6, 9, and 12 months. The main outcomes include feasibility measures like recruitment and adherence, as well as exploratory measures of cognitive and physical function changes over the year-long study.
CONDITIONS
Brief Title
Train Your Brain Fitness SC: An Exercise Intervention for People With Cognitive Impairments
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult aged over 18 years
- Medical diagnosis of mild to moderate cognitive impairment
- Medical clearance from referring provider for exercise
- Able to follow two-step commands
You will not qualify if you...
- Significant pain with movement rated over 5 out of 10
- Severe balance impairments or lack of independence on and off exercise equipment as judged by a physical therapist at intake
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 screening and enrollment visit (in-person)
Duration - 12 weeks
Participants engage in a personalized exercise program including moderate intensity endurance, strength, balance, agility, and mobility training. The program is delivered either with real-time coaching at a fitness center or with support from a personal trainer for up to 7 visits and additional independent exercise.
Twice weekly exercise sessions; up to 7 personal trainer visits for distance group; bi-weekly check-ins via phone, text, or email for distance group; in-person coaching for in-person group
Duration - Up to 12 months
Participants are followed to assess individual outcomes including cognitive processing, cardiovascular endurance, mobility, balance, grip strength, and perception of cognition over 12 months.
Assessments at baseline, 3, 6, 9, and 12 months
Trial Site Locations
Total: 2 locations
1
Arnold School of Public Health
Columbia, South Carolina, United States, 29208
Actively Recruiting
2
Sumter YMCA
Sumter, South Carolina, United States, 29150
Actively Recruiting
Research Team
E
Elizabeth Regan, PhD
A
Amberly Osteen
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
Frequently Asked Questions
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