Actively Recruiting

Phase 2
Age: 18Years +
All Genders
NCT07219875

Training Reward Responsiveness Through Virtual Reality

Led by University of California, Los Angeles · Updated on 2026-05-07

80

Participants Needed

1

Research Sites

99 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to compare the effects of Virtual Reality-Reward Training (VR-RT) with an active control condition, Virtual Reality-Memory Training (VR-MT), on positive affect and other clinical symptoms. VR-Reward Training is a novel intervention aimed at enhancing savoring of positive experiences among individuals with depression and low positive affect through guided imaginal recounting following immersion in positive VR experiences. The current study tests an enhanced version of this training using improved virtual reality technology. Target enrollment is 80 participants with low positive affect, depression, and impaired functioning, who are at least 18 years old, who will be randomly assigned to 7 weeks of either Virtual Reality-Reward Training (VR-RT) or Virtual Reality-Memory Training (VR-MT). Participants will complete in-person VR sessions, laboratory assessments, self-report questionnaires as part of the study. A subset of 8 participants randomly assigned to VR-RT will complete fMRI scans and EMA surveys. The total length of participation is around 3 months.

CONDITIONS

Official Title

Training Reward Responsiveness Through Virtual Reality

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • At least 18 years old
  • Fluent in written and spoken English
  • Score of 8 or higher on the DASS-21 depression subscale
  • Score of 27 or lower on the PANAS-P
  • Score of 11 or higher on the WSAS
Not Eligible

You will not qualify if you...

  • History of bipolar disorder, psychosis, intellectual disability, or organic brain damage
  • Substance use disorder within the past 6 months
  • Current use of psychotropic medications
  • Currently pregnant or planning pregnancy
  • Frequent motion sickness reported
  • Seizures in the last year or diagnosis of epilepsy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of California, Los Angeles

Los Angeles, California, United States, 90095

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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