Actively Recruiting
Tranexamic Acid in Nasal Mohs Reconstruction
Led by Vanderbilt University Medical Center · Updated on 2025-08-19
100
Participants Needed
1
Research Sites
114 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study will be a prospective randomized control trial to evaluate the effects of subcutaneously administered TXA among patients undergoing nasal Mohs reconstruction with local flaps at VUMC.
CONDITIONS
Official Title
Tranexamic Acid in Nasal Mohs Reconstruction
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults at least 18 years old undergoing local flap reconstruction of a nasal defect after Mohs micrographic surgery
- Reconstruction performed by specified surgeons at Vanderbilt University Medical Center
- No other facial plastic or sinus surgery performed at the same time
- Must not meet any of the exclusion criteria
You will not qualify if you...
- Known allergy to tranexamic acid (TXA)
- Intracranial bleeding
- Known defective color vision
- History of venous or arterial thromboembolism
- History of coagulation disorder
- Active thromboembolic disease
- Severe renal impairment or chronic kidney disease
- History of acute myocardial infarction
- History of stroke
- History of seizure
- History of liver failure
- Preoperative lab results showing low platelets (less than 150,000) or increased bleeding risk (PT over 45, INR over 1.2)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Vanderbilt University Medical Center
Nashville, Tennessee, United States, 37232
Actively Recruiting
Research Team
C
Connie Ma, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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