Actively Recruiting
Pilot Study of Trans-radial Superior Rectal Artery Embolisation for Hemorrhoid Treatment
Led by University Hospitals of North Midlands NHS Trust · Updated on 2025-09-03
20
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to evaluate the safety and effectiveness of transarterial embolisation for treating symptomatic hemorrhoids in an elective setting. Endovascular embolisation is already common for acute bleeding hemorrhoids when surgery isn't possible or has failed. This pilot study seeks to provide evidence that this less invasive treatment can be a good alternative to conventional surgery, potentially reducing complications and costs for healthcare systems under financial pressure. Participants will undergo a day procedure called trans-radial superior rectal artery embolisation performed under local anaesthetic. The study will recruit 20 selected patients with grade II-IV hemorrhoid disease who either do not wish to have surgery or have persistent symptoms despite recent surgery. This procedure involves using fluoroscopic guidance to deliver embolisation through the radial artery, aiming to reduce symptoms by blocking blood flow to the hemorrhoids. During the study, participants will be assessed with validated symptom scoring systems and routine blood tests at the initial visit. They will be followed for 24 months after the procedure to monitor symptom changes and safety outcomes. Researchers will record procedural details, radiation dose, and contrast volume, as well as compare costs over three years. The long-term goal is to build a national registry of such procedures, with total follow-up planned for three years.
CONDITIONS
Brief Title
Trans-radial Superior Rectal Artery Embolisation for Haemorrhoids
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with grade II-IV hemorrhoid disease with recurrent or active bleeding
- Patients who do not wish to undergo surgery for their symptoms
- Patients with symptoms despite recent hemorrhoid surgery
- Patients willing and able to give fully informed consent
- Patients aged 18 years or older
You will not qualify if you...
- Patients not fit for surgery
- Patients with significant anorectal comorbidities such as cancer, fistula, or abscesses
- Patients unable to sign the informed consent form
- Pregnant patients
- Patients with a history of significant colorectal disease or previous colectomy
- Patients with a history of allergic reaction to x-ray contrast
- Patients currently involved in other research studies
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Single day procedure
Participants undergo a day case procedure called trans-radial superior rectal artery embolisation for haemorrhoids performed under local anaesthetic.
1 procedure visit (in-person)
Duration - Up to 3 years
Participants are monitored for safety and long-term effects of the treatment over 3 years.
Scheduled follow-up visits over 3 years
Trial Site Locations
Total: 1 location
1
University Hospitals of North Midlands NHS Trust
Stoke-on-Trent, United Kingdom
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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