Actively Recruiting

Phase Not Applicable
Age: 18Years - 85Years
All Genders
NCT06773780

Transcatheter Aortic Valve Implantation: Comparison of the Effects of Ultrasound-Guided Pericapsular Nerve Group Block and Fascia Iliaca Block on Postoperative Analgesia Management

Led by Medipol University · Updated on 2025-12-02

60

Participants Needed

1

Research Sites

98 weeks

Total Duration

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AI-Summary

What this Trial Is About

Aortic Stenosis (AS) is the most common valvular pathology, particularly prevalent in advanced age, and Transcatheter Aortic Valve Implantation (TAVI) has become a crucial treatment option for high-risk patients who are not suitable for surgery. This minimally invasive approach has demonstrated successful clinical outcomes in patients deemed ineligible for surgical procedures. Patient selection criteria and advancements in operative techniques are critical for achieving successful TAVI outcomes. While the transfemoral approach is the most commonly used method, alternative techniques such as transapical, transaxillary, transcarotid, and transaortic approaches are also available. The Pericapsular Nerve Group Block (PENG) targets the femoral and accessory obturator nerves, providing analgesia to the anterior hip without causing motor block. The Fascia Iliaca Block (FIB), on the other hand, provides broader analgesic coverage by affecting the lateral femoral cutaneous, obturator, and femoral nerves. This study aims to compare PENG block, FIB, and local infiltration anesthesia in TAVI patients regarding sedation requirements during the procedure and postoperative analgesia management. Additionally, pain scores, motor block presence, opioid consumption, and side effects will be assessed. The study seeks to identify optimal strategies to enhance patient comfort and safety during TAVI procedures.

CONDITIONS

Official Title

Transcatheter Aortic Valve Implantation: Comparison of the Effects of Ultrasound-Guided Pericapsular Nerve Group Block and Fascia Iliaca Block on Postoperative Analgesia Management

Who Can Participate

Age: 18Years - 85Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients scheduled for Transcatheter Aortic Valve Implantation (TAVI)
  • Aged between 18 and 85 years
  • American Society of Anesthesiology (ASA) physical status II-IV
Not Eligible

You will not qualify if you...

  • History of bleeding diathesis
  • Use of anticoagulant therapy
  • History of chronic pain prior to surgery
  • Multiple trauma
  • Conditions where pain assessment cannot be performed (e.g., dementia)
  • Patients operated under spinal or epidural anesthesia
  • Presence of infection in the region where the block will be applied
  • Refusal to consent to the procedure

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Medipol University

Istanbul, Turkey (Türkiye)

Actively Recruiting

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Research Team

B

Burak Ömür

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

3

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