Actively Recruiting

Age: 18Years +
All Genders
NCT06589063

Transcatheter Aortic Valve Replacement in Severe Low Flow, Low Gradient Aortic Stenosis

Led by University of Salerno · Updated on 2026-04-07

1350

Participants Needed

1

Research Sites

721 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

LOW-TAVR is a real-world, retrospective and prospective, multicenter Italian registry aimed at evaluating the characteristics and clinical outcomes of patients with severe low flow, low gradient aortic stenosis undergoing transcatheter aortic valve replacement (TAVR) and, in particular: * risk factors * gender differences * comorbidities * pharmacological treatment * TAVR procedural characteristics * periprocedural and in-hospital complications * clinical outcome at 30-day, 1-year, 2-year and 5-year follow-up

CONDITIONS

Official Title

Transcatheter Aortic Valve Replacement in Severe Low Flow, Low Gradient Aortic Stenosis

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with severe low flow, low gradient aortic stenosis according to current European Society of Cardiology guidelines
  • Age 18 years or older
  • Provided written informed consent
Not Eligible

You will not qualify if you...

  • Pseudo-severe or non-confirmed severe aortic stenosis
  • Referred for medical treatment or undergoing surgery instead of TAVR

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Salerno

Salerno, Italy, 84131

Actively Recruiting

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Research Team

G

Gennaro Galasso, MD, PhD

CONTACT

A

Angelo Silverio, MD, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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