Actively Recruiting
Transcatheter Arterial Micro-Embolization (TAME) Using Nexsphere-F in Patients With Knee Degenerative Osteoarthritis
Led by Next Biomedical Co., Ltd. · Updated on 2025-04-02
20
Participants Needed
1
Research Sites
110 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Among knee degenerative osteoarthritis patients aged 50 or older, it will prove the therapeutic effect and safety of Nexsphere-F embolization for patients who need additional treatment because pain is not controlled even if conventional treatments are taken.
CONDITIONS
Official Title
Transcatheter Arterial Micro-Embolization (TAME) Using Nexsphere-F in Patients With Knee Degenerative Osteoarthritis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 50 years or older
- Kellgren-Lawrence grade 2 to 3 knee osteoarthritis based on X-ray within last 12 months
- Visual Analog Scale (VAS) pain score above 50mm
- Ongoing treatment with glucosamine chondroitin sulfate, rehabilitation exercises, or hyaluronic acid joint injections for at least 12 weeks
- Agreement to maintain existing medications during the study without adding new treatments for knee osteoarthritis pain
You will not qualify if you...
- Local infection
- Life expectancy less than six months
- Symptoms of lower extremity vascular disease such as claudication or ischemic rest pain
- Diagnosis of rheumatism or infectious arthritis
- History of knee arthroplasty
- Knee microfracture surgery within the past 10 years
- INR greater than 2.5 or platelet count below 30,000
- Allergy causing anaphylaxis to iodine
- Renal dysfunction with eGFR less than 45 within last 60 days
- Contraindication to MRI
- Pregnancy
- Any condition deemed inappropriate for participation by the researcher
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Severance Hospital
Seoul, Seodaemun-gu, South Korea, 03722
Actively Recruiting
Research Team
H
Hyuckmin Kwon
CONTACT
S
Sungmo Moon
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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