Actively Recruiting
Transcranial Direct Current Stimulation for Depression
Led by Taipei Veterans General Hospital, Taiwan · Updated on 2024-01-02
30
Participants Needed
1
Research Sites
329 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Several studies have shown that tDCS is valuable and safe options to improve depressive symptoms in adult patients . However, regarding the tDCS to treat depression in elderly population, only few studies have been reported, and there is no consensus among them. To our knowledge, prefrontal cortex tDCS could be reasonably safe and efficient options for the treatment of several psychiatric illnesses in a population presenting resistance to and/or intolerance of pharmacotherapy . Moreover, the safety tolerability profile of tDCS is a strong argument in favour of exploring their use in the depressed population. Therefore, current study will investigate the efficacy and safety of prefrontal tDCS used as additive treatment in patients with LLD.
CONDITIONS
Official Title
Transcranial Direct Current Stimulation for Depression
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participants who meet the criteria of major depression defined by DSM-5 criteria
- Participants who are non-responders to antidepressants at an adequate dose for at least 4 weeks in the current episode, or cannot tolerate adverse effects of antidepressants
- Ambulatory participants, with or without any aiding device
You will not qualify if you...
- Urgent risk of suicide or severe depression
- History of ineffectiveness with tDCS
- Clinical contraindications to tDCS or MRI, such as brain lesions, intracranial implants, scalp or brain metal, or scalp tattoos
- Any unstable medical condition
- History of epilepsy
- History of substance use within one year
- Diagnosis of dementia or psychotic disorder
- Any condition making the participant unsuitable for the study per physician assessment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
TaipeiVGH
Taipei, Taiwan
Actively Recruiting
Research Team
M
Mu-N Liu, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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