Actively Recruiting

Phase Not Applicable
Age: 50Years - 80Years
All Genders
NCT06818240

Transcranial Direct Current Stimulation Enhances Dual-task Performance in Stroke

Led by The Hong Kong Polytechnic University · Updated on 2025-02-10

50

Participants Needed

1

Research Sites

17 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Stroke often impairs lower limb control, resulting in gait abnormalities and difficulties in dual-task performance, such as walking while engaging in cognitive activities. This study examines the effects of a single session of transcranial direct current stimulation (tDCS) targeting the left dorsolateral prefrontal cortex (DLPFC) on dual-task walking performance in individuals with chronic stroke. Using a cross-over design, participants will undergo two sessions (active or sham tDCS, 7 ± 2 days apart) of stimulation at 2 mA for 30 minutes. Walking performance will be measured using single and dual-task conditions combining motor (e.g., 20 m walk) and cognitive tasks (e.g., word association, random number recall). Primary outcomes include walking speed (m/s), stride length (m), and dual-task cost (DTC) for mobility and cognitive speed. The study aims to evaluate tDCS as a potential tool to reduce DTC, improve dual-task performance, and improve daily function and quality of life in stroke survivors. Results may guide the development of tailored dual-task interventions in stroke rehabilitation.

CONDITIONS

Official Title

Transcranial Direct Current Stimulation Enhances Dual-task Performance in Stroke

Who Can Participate

Age: 50Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 50 and 80 years
  • At least 6 months since first-ever stroke with weakness on one side of the body
  • Ability to walk independently for at least 10 meters without walking aids
  • Mini-Mental State Examination score of 24 or higher
Not Eligible

You will not qualify if you...

  • Unstable medical conditions such as heart failure, uncontrolled high blood pressure, or cancer
  • Other health problems that affect walking
  • History of epilepsy or presence of metal implants that prevent tDCS use
  • History of head injury, head surgery, or problems with lower limb bones or joints

AI-Screening

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Trial Site Locations

Total: 1 location

1

The Hong Kong Polytechnic University

Hong Kong, China, Hong Kong

Actively Recruiting

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Research Team

S

Shamay SM NG, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

TREATMENT

Number of Arms

2

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