Actively Recruiting

Phase Not Applicable
Age: 21Years - 80Years
All Genders
Healthy Volunteers
NCT04142866

Transcranial Direct Current Stimulation (tDCS) With Verb Network Strengthening Treatment (VNeST) in Chronic Aphasia

Led by City University of New York · Updated on 2025-01-07

30

Participants Needed

1

Research Sites

103 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to assess changes in language abilities of participants with chronic, post-stroke aphasia following an 8-week therapy period combined with brain stimulation. The investigators use a stimulation method called transcranial direct current stimulation (tDCS). The investigators cover two electrodes in damp sponges, place them on the scalp, and pass a weak electrical current between them. Some of this current passes through the brain and can change brain activity. One electrode is placed over language areas a bit above and in front of the left ear. The other is placed on the forehead above the right eye. Stimulation is provided twice a week for 8 weeks during aphasia therapy. The investigators believe that this stimulation may increase the effectiveness of therapy.

CONDITIONS

Official Title

Transcranial Direct Current Stimulation (tDCS) With Verb Network Strengthening Treatment (VNeST) in Chronic Aphasia

Who Can Participate

Age: 21Years - 80Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Right handed (pre-stroke for participants with aphasia)
  • High school education or equivalent
  • Native English fluency without early second language exposure (before age 10)
  • Ability to perform the required discourse and MRI tasks
  • For participants with aphasia: single-event left hemisphere stroke more than 6 months prior to enrollment
  • For participants with aphasia: diagnosis of aphasia confirmed by Western Aphasia Battery-Revised
  • For participants with aphasia: no other speech therapy during the 20-week study period
  • For participants with aphasia: ability to perform the required therapy tasks
Not Eligible

You will not qualify if you...

  • Failed vision or hearing screening
  • MRI contraindications including pacemaker
  • Pregnancy
  • History of seizure or change in seizure medication in past 12 months
  • History of speech/language, psychiatric, or neurological disorder, or serious medical condition (except chronic stroke comorbidities for aphasia participants)
  • For participants with aphasia: unmodifiable hairstyle preventing electrode scalp contact
  • For participants with aphasia: sensitive scalp by self-report

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

City University of New York

New York, New York, United States, 10016

Actively Recruiting

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Research Team

E

E. Susan Duncan, PhD, CCC-SLP

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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