Actively Recruiting

Phase Not Applicable
Age: 45Years +
All Genders
Healthy Volunteers
NCT06228573

Transcranial Direct Current Stimulation and Yoga for Knee Osteoarthritis

Led by McMaster University · Updated on 2024-11-21

68

Participants Needed

3

Research Sites

62 weeks

Total Duration

On this page

Sponsors

M

McMaster University

Lead Sponsor

T

The Arthritis Society, Canada

Collaborating Sponsor

AI-Summary

What this Trial Is About

People with knee arthritis often experience constant pain, and current treatments aren't very effective. This can lead to limited movement and more health problems. Knee arthritis is a big part of healthcare costs in Canada, and its pain is a major reason people see doctors. The pain is linked to complex nervous system changes, making current treatments, like exercise, not very successful. To address this, researchers suggest a new approach combining two things: a brain stimulation technique called Transcranial Direct Current Stimulation (tDCS) and yoga. TDCS helps with pain by changing how the brain works, and yoga, a safe practice, focuses on overall well-being. Together, the investigators aim to improve how the nervous system works from top to bottom. The research project wants to change how the arthritis pain is being managed by focusing on how it works. The investigators plan to test this combo in a study comparing real tDCS plus yoga with fake tDCS plus yoga. The investigators will look not only at pain but also at other measures related to pain and how the nervous system works. This new mix could be a meaningful way to reduce pain for people with knee arthritis.

CONDITIONS

Official Title

Transcranial Direct Current Stimulation and Yoga for Knee Osteoarthritis

Who Can Participate

Age: 45Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 45 years or older
  • Community dwelling adults from Sherbrooke, Quebec, Hamilton, and London, Ontario meeting NICE criteria for knee osteoarthritis
  • Diagnosis of knee osteoarthritis OR experiencing movement-related knee joint pain with no morning stiffness or stiffness lasting 30 minutes or less
  • Experiencing an average pain intensity of 3 or higher on a 0-10 scale in the past month
Not Eligible

You will not qualify if you...

  • Presence of systemic inflammatory arthritis
  • Knee injection received within the past 3 months
  • Unable to independently get up and down from the floor
  • Lower limb trauma or surgery within the last 6 months
  • Current participation in another osteoarthritis clinical trial
  • Use of mobility aids
  • Currently receiving care for knee osteoarthritis pain such as physiotherapy
  • Planned absences longer than 1 week during the study
  • Contraindications to transcranial direct current stimulation, including neurological or neuropsychiatric conditions
  • History of brain surgery or brain tumor
  • Presence of metallic implants
  • Epilepsy or history of substance abuse or dependence
  • Cochlear or ocular implants
  • Presence of a pacemaker or cardiac defibrillator
  • Eczema on the scalp

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 3 locations

1

McMaster University

Hamilton, Ontario, Canada, L8S1C7

Actively Recruiting

2

University of Western Ontario

London, Ontario, Canada, N6A 3K7

Actively Recruiting

3

Université de Sherbrooke

Sherbrooke, Quebec, Canada, J1K 2R1

Actively Recruiting

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Research Team

L

Lisa Carlesso, PhD

CONTACT

G

Guillaume Leonard, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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