Actively Recruiting
TRAnscranial Doppler CErebral Blood Flow and Cognitive IMPAIRment in Heart Failure
Led by John Paul II Hospital, Krakow · Updated on 2022-02-22
300
Participants Needed
1
Research Sites
313 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
TRACE-IMPAIR is a prospective, clinical study of consecutive patients that evaluates the relationship between heart failure (HF) and cognitive impairment in relation to carotid and cerebral flow. The carotid and cerebral flow will be assessed using Doppler ultrasonography, and cognitive function will be estimated during routine neuropsychological tests. It is an observational, three(natural)-group, single-center study. It is also an Academic Registry - the scientific activity of the Faculty of Medicine, Collegium Medicum, Jagiellonian University, and John Paul II Hospital.
CONDITIONS
Official Title
TRAnscranial Doppler CErebral Blood Flow and Cognitive IMPAIRment in Heart Failure
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Clinically stable patients (NYHA I-III symptoms) with heart failure for at least 6 months of ischemic, inflammatory, or genetic cardiomyopathy origin
- Signed informed consent form
- Consent to undergo echocardiography, carotid and transcranial Doppler sonography, and neuropsychological tests (MMSE and MoCA)
You will not qualify if you...
- Severe, irreversible diseases such as advanced cancer
- Previously diagnosed dementia including severe dementia with MMSE and MoCA scores below 10
- Psychiatric conditions affecting cognitive function
- Acute or decompensated heart failure
- Reversible causes of heart failure such as tachyarrhythmic, peripartum or toxic cardiomyopathy, acute myocarditis, or acute myocardial infarction
- Aortic stenosis
- Stroke within the last 3 months
- Lack of suitable transcranial Doppler acoustic window
- Echocardiographic views that prevent adequate measurements
- Anemia with hemoglobin less than 8 g/dl
- Abuse of alcohol or psychoactive substances
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Department of Cardiac and Vascular Diseases, The John Paul II Hospital
Krakow, MP, Poland, 31-202
Actively Recruiting
Research Team
P
Piotr Musialek, MD, DPhil
CONTACT
K
Karolina Dzierwa, MD, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here