Actively Recruiting
Transcranial Doppler for Internal Carotid Artery Stenting (TCD-ICAS)
Led by General Hospital of Shenyang Military Region · Updated on 2026-03-25
232
Participants Needed
1
Research Sites
35 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Carotid artery stenting (CAS) prevents stroke but carries risks of perioperative cerebral embolism. Transcranial Doppler (TCD) ultrasound can detect microemboli during CAS and may offer therapeutic benefits through ultrasound-enhanced thrombolysis. Trials like SONOBUSTER and SONOBIRDIE suggest TCD reduces new brain infarctions during carotid procedures. The TCD-ICAS trial will investigate whether TCD application during and after CAS reduces perioperative cerebral emboli and improves outcomes.
CONDITIONS
Official Title
Transcranial Doppler for Internal Carotid Artery Stenting (TCD-ICAS)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 40 years or older
- Diagnosis of severe stenosis of the internal carotid artery
- Planned for carotid artery stenting procedure
- Modified Rankin Scale score of 2 or less
- Adequate temporal bone windows for Transcranial Doppler with detectable middle cerebral artery blood flow
- Signed informed consent by patient or legally authorized representative
You will not qualify if you...
- Severe infections or serious diseases of the liver, kidney, blood, or endocrine system
- Intracranial hemorrhage within 90 days before enrollment
- Severe blood disorders or major coagulation problems
- Pregnant or breastfeeding women
- Participation in another clinical trial within the past 3 months or ongoing participation
- Any condition considered unsuitable by the investigator for study participation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Department of Neurology, General Hospital of Northern Theater Command
Shenyang, China, 110016
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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