Actively Recruiting
Transcranial Magnetic Stimulation for Chemotherapy-Induced Peripheral Neuropathy in Breast and Gynecologic Cancer Survivors
Led by University of Utah · Updated on 2025-11-21
19
Participants Needed
1
Research Sites
159 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this study is to evaluate the change in pain scores among patients with chemotherapy-induced peripheral neuropathy after receiving treatment with repetitive transcranial magnetic stimulation (rTMS).
CONDITIONS
Official Title
Transcranial Magnetic Stimulation for Chemotherapy-Induced Peripheral Neuropathy in Breast and Gynecologic Cancer Survivors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Female subjects aged 18 years or older
- Histologically confirmed breast or gynecologic cancer
- Neuropathic pain developed with or within one month after treatment with platinum-based drugs, taxanes, or vinca alkaloids
- Pain score of 4 or more on the Pain Numeric Rating Scale
- Score of 3 or more on the Douleur Neuropathique 4 questionnaire
- Persistent neuropathic pain and current use of at least one neuropathic pain medication
- Stable dose of neuropathic pain medication for at least 6 weeks prior to enrollment
- Negative pregnancy test or post-menopausal status as defined by amenorrhea for 12 months or surgical sterilization
- Agreement to use highly effective contraception if of childbearing potential
- Ability to provide informed consent and willingness to sign consent form
You will not qualify if you...
- Evidence of recurrent breast or gynecologic cancer at enrollment
- Current or planned chemotherapy treatment
- History of seizure, epilepsy, or other conditions affecting safety or participation
- Neuropathic pain unrelated to systemic cancer therapy (e.g., diabetic neuropathy, HIV-induced neuropathy)
- Presence of implantable devices incompatible with rTMS (e.g., spinal cord stimulators, deep brain stimulators)
- Use of medications that significantly lower seizure threshold
- Any condition contraindicating participation due to safety or compliance concerns
- History of recent suicide attempt or active suicidal ideation
- Medical, psychiatric, cognitive, or other conditions impairing consent or protocol compliance
- Enrollment in another study that may interfere with participation or cause undue burden
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Huntsman Cancer Institute at University of Utah
Salt Lake City, Utah, United States, 84112
Actively Recruiting
Research Team
J
Janna Espinosa
CONTACT
N
Newaj Abdullah, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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