Actively Recruiting
Transcranial Magnetic Stimulation in Misophonia
Led by Icahn School of Medicine at Mount Sinai · Updated on 2025-09-09
60
Participants Needed
1
Research Sites
43 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of the project is to assess the efficacy of parietal transcranial magnetic stimulation in misophonia. N=60 participants will undergo two transcranial magnetic stimulation sessions: one inhibitory and another excitatory. During both sessions, the parietal region will be stimulated. Participants will perform computerized tasks immediately before and after the stimulation, while EEG, heart rate, and skin temperature will be recorded. These recordings will be used to assess if TMS can be used to improve tolerance to misophonia triggers.
CONDITIONS
Official Title
Transcranial Magnetic Stimulation in Misophonia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Hypersensitive to presence of a specific sound, which may be accompanied by irritation, anger/outbursts, or fear.
- Must be between the ages of 18 - 55.
- Must be fluent in English since the study's instructions, surveys, and tasks will be in English.
You will not qualify if you...
- Axis I Psychiatric condition, past or present, as defined in DSM-V.
- Disability or medical condition that prohibits completion of study. Participants must be able to complete all study procedures to ensure optimal conditions for data analysis.
- Central Nervous System (CNS) disease, such as history of brain abnormalities (e.g., neoplasms, subarachnoid cysts), cerebrovascular disease, infectious disease (e.g., abscess), or other neurological diseases, history of head trauma (defined as loss of consciousness>3 min), or history of seizures without a resolved etiology.
- Recent or regular use of psychotropic medication (e.g., amitriptyline for migraines).
- Recent use of drugs of abuse.
- Presence of any mental implants in the head.
- Pregnant or lactating.
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Mount Sinai West
New York, New York, United States, 10022
Actively Recruiting
Research Team
S
Shama Patel
CONTACT
P
Parul Jain, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
2
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