Actively Recruiting
Transcranial Pulse Stimulation for Alzheimer's Disease
Led by Chinese University of Hong Kong · Updated on 2025-09-16
40
Participants Needed
1
Research Sites
45 weeks
Total Duration
On this page
Sponsors
C
Chinese University of Hong Kong
Lead Sponsor
A
Asia Pacific Institute of Healthy ageing
Collaborating Sponsor
AI-Summary
What this Trial Is About
TPS is a non-invasive therapeutic modality that uses focused, low-energy pulse stimulation to stimulate tissue regeneration and reduce inflammation. In the context of neurological disorders, it is hypothesized that TPS can modulate neuronal activity, enhance synaptic plasticity, and reduce neuroinflammation. It is a relatively new application in neurological disease treatment and is still under intense investigation.
CONDITIONS
Official Title
Transcranial Pulse Stimulation for Alzheimer's Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults clinically diagnosed with early-stage Alzheimer's Disease (stage 2-6a by Functional Assessment Staging Test)
- Have mental capacity to give informed consent as assessed by a geriatrician
- Aged between 60 and 90 years old
- Able to give informed consent with assistance, witnessed and signed by a family caregiver
You will not qualify if you...
- Cannot understand Chinese
- Mentally incapacitated or unable to provide informed consent
- Unable to remain still for 30 minutes
- No available family caregiver to answer questionnaires
- Alcohol or substance dependence
- Major neurological conditions such as brain tumor or brain aneurysm
- Presence of metal implants in the brain
- Hemophilia or other blood clotting disorders
- History of thrombosis
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Department of Medicine & Therapeutics, Faculty of Medicine, The Chinese UNiversity of Hong Kong
Hong Kong, Hong Kong
Actively Recruiting
Research Team
K
KI SUM CHU, PhD candidate
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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