Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06730438

Transcranial Pulse Stimulation. a Potential Treatment for Early Dementia

Led by Francesca Pistoia · Updated on 2024-12-16

100

Participants Needed

2

Research Sites

82 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Alzheimer's Disease (AD) is characterized by the absence of treatments to slow, stop, or reverse its course, with patients finally losing cognitive functions, skills and independence. It is a chronic degenerative disease with high social and medical burden worldwide: AD ranked third among neurological disorders in terms of disability-adjusted life years (DALY) rates. The primary aim of the research protocol is to improve care for patients with AD, by implementing, with an innovative method, the currently available repertoire of neuromodulation techniques. For this aim, we will investigate whether Transcranial Pulse Stimulation (TPS) may induce cognitive improvement in patients with an early stage of dementia.

CONDITIONS

Official Title

Transcranial Pulse Stimulation. a Potential Treatment for Early Dementia

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age over 18 years
  • Diagnosis of early dementia according to current international guidelines
  • Dementia duration of at least 12 months
  • Willingness and consent to participate in the study
Not Eligible

You will not qualify if you...

  • Medical instability that interferes with neurological assessment
  • Any contraindication to preliminary MRI needed for neuronavigation
  • Comorbidities that may affect cognitive status
  • Any contraindication to Transcranial Pulse Stimulation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

San Salvatore Hospital

L’Aquila, Italy, Italy, 67100

Actively Recruiting

2

San Salvatore Hospital

L’Aquila, Italy, Italy, 67100

Actively Recruiting

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Research Team

F

Francesca Pistoia, MD, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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