Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06734013

Transcriptomics as an Aid in the Histological Diagnosis of Acute Rejection After Liver Transplantation

Led by IRCCS Azienda Ospedaliero-Universitaria di Bologna · Updated on 2024-12-16

40

Participants Needed

1

Research Sites

32 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The primary objective of this exploratory study is to identify genes associated with acute rejection in liver transplant patients. To this end, a panel of acute rejection indicator genes (both humoral and cell-mediated) will be selected from results published in the literature and applied to biological material derived from biopsies. The secodnary objective is to identify genes associated with the diagnosis of humoral acute rejection and those associated with the diagnosis of cell-mediated acute rejection.

CONDITIONS

Official Title

Transcriptomics as an Aid in the Histological Diagnosis of Acute Rejection After Liver Transplantation

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with a diagnosis of post-OLT rejection prior to the visit at which they will be enrolled, with tissue available for RT-PCR investigations
  • Age 5 18 years
  • Informed consent
Not Eligible

You will not qualify if you...

  • Age <18 years

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

IRCCS Azienda Ospedaliero-Universitaria di Bologna

Bologna, Italy, 40138

Actively Recruiting

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Research Team

D

Deborah Malvi, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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