Actively Recruiting

Phase 1
Phase 2
Age: 18Years - 65Years
All Genders
NCT06544447

Transcutaneous Auricular Vagus Nerve Stimulation in Dry Eye Disease With Meibomian Gland Dysfunction

Led by Beijing Tongren Hospital · Updated on 2024-08-09

135

Participants Needed

1

Research Sites

174 weeks

Total Duration

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AI-Summary

What this Trial Is About

Objective: To evaluate the effect of transcutaneous auricular vagus nerve stimulation (taVNS) for the patients with dry eye disease with meibomian gland dysfunction. Methods: We enrolled 270 patients at Beijing Tongren Hospital. All treatments were self-administered by the patients at home after training at the hospital. Patients completed questionnaires at baseline, 1 month, 3 months, and 6 months. OSDI score, TBUT, OPAS, NPSI-eye, and Schirmer I expressibility and secretion score to evaluate the therapeutic effects. A difference of P \< 0.05 was considered statistically significant.

CONDITIONS

Official Title

Transcutaneous Auricular Vagus Nerve Stimulation in Dry Eye Disease With Meibomian Gland Dysfunction

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 to 65 years
  • Clinical diagnosis of dry eye disease with meibomian gland dysfunction
Not Eligible

You will not qualify if you...

  • History of depression, tumors, thyroid disease, diabetes, or cardiac diseases
  • History of ear, nose, or throat surgery
  • Pregnant or lactating women

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

China Beijing TongRen Hospital, Capital Medical University Beijing, China

Beijing, Beijing Municipality, China, 100730

Actively Recruiting

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Research Team

D

Dong Wu, Doctor

CONTACT

H

Haihong Lian, Doctor

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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