Actively Recruiting
Transcutaneous Auricular Vagus Nerve Stimulation for Persistent Post-concussion Symptoms
Led by University of Liege · Updated on 2025-06-12
48
Participants Needed
1
Research Sites
104 weeks
Total Duration
On this page
Sponsors
U
University of Liege
Lead Sponsor
U
University Hospital Sart Tilman, Liege
Collaborating Sponsor
AI-Summary
What this Trial Is About
Persistent post-concussive symptoms (PPCS) affect a significant proportion of individuals following a concussion, leading to debilitating impacts on their quality of life and work capacity. Currently, effective treatments for PPCS are limited, despite their lasting and debilitating impact. Transcutaneous auricular vagus nerve stimulation (taVNS), a non-invasive neuromodulation technique, holds promise as a therapeutic option by leveraging the bottom-up modulation of brain activity via the auricular branch of the vagus nerve. This study aims to evaluate the neurophysiological and clinical effects of taVNS on brain activity and symptomatology in patients with PPCS through a randomized, controlled, double-blind trial.
CONDITIONS
Official Title
Transcutaneous Auricular Vagus Nerve Stimulation for Persistent Post-concussion Symptoms
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 65 years
- Diagnosis of concussion between 4 weeks and 1 year before enrollment
- Score of 16 or higher on the Rivermead Post-Concussion Questionnaire
- Intact skin at the site where electrodes will be placed
You will not qualify if you...
- History of chronic neurological or psychological disorders untreated in the last 6 months
- Pregnant or breastfeeding
- Have an active implant such as a pacemaker or cochlear implant
- History of myocardial infarction or heart rhythm problems
- Consumed more than 14 alcoholic drinks per week or used drugs more than once per week in the past 6 months
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University Hospital of Liège
Liège, Liège, Belgium, 4000
Actively Recruiting
Research Team
M
Mélanie Louras, MSc
CONTACT
A
Aurore Thibaut, PT, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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